Shiseido - After 20 years of research, Shiseido has created a new world-first: Ultimune. Ultimune works from the inside to strengthen, repair and reinforce the skin's immunity to resist the impact of future ageing. Shiseido has developed the first complex that directly targets Langerhans cells - the immune power source behind healthy, damage free skin. Ultimune ComplexTM increases the function of Langerhans cells by 64%, activating the skin's power to defend itself against all kinds of skin damage. Make ULTIMUNE your daily dose of beauty *Tested on over 200 women, self evaluation.